Release Kinetics of Monomers from Dental Composites Containing Fluoride-Doped Calcium Phosphates

This study analyse the type of release kinetic specific monomers from dental resin composites containing various fluoride-doped calcium phosphates. The behavior urethane dimethacrylate (UDMA), ethoxylated bisphenol-A (bis-EMA) and 1.6-hexanediol ethoxylate diacrylate (HEDA) was evaluated over a period 35 days. Two tailored phosphates doped with different concentrations fluoride salts (VS10% VS20%) were prepared incorporated in matrix at to generate range experimental composites. kinetics characterized using mathematical models such as zero-order, first-order, Peppas Higuchi models. results showed that first-order model best described kinetics. UDMA HEDA exhibited significant differences compared bis-EMA day 1, while no observed between HEDA, except on 35, when higher rate than HEDA. When comparing each monomer, VS20-R20% had highest total percentage, 3.10 ± 0.25%, whereas composite VS10-R5% lowest 1.66 0.08%. influenced by composition presence sodium phosphate played role maximum amounts monomer released. In conclusion, tested followed behaviour, an initial rapid decreased time. VS10-R10% release, suggesting its potential favourable reduced elution. These findings contribute understanding provide insights for development resin-based bioactive materials.